1. Science and clinical studies: DMAE is considered a tertiary amine and a precursor of choline. At concentration of 1% to 5% when applied to facial skin, DMAE have been shown to produce and increase tone in about 20 to 30 minutes. Half-and full-face studies applied over 16 weeks to one year have been shown to produce periorbital tightening as well as tightening in the molar and mandible regions. These results appear to reverse when product application is stopped after eight weeks (36).
2. Key benefits: Enhances muscle tonality and can act as a penetration enhancer.
3. Primary adverse effects: Low toxicity and no side effects.
4. Practical applications in dermatology: Non-surgical treatment to correct loss facial anatomic positions.