Some facial masks, particularly masks that are part of a skin-care routine for acne, contain sulfur, which can have some benefit as a disinfectant for breakouts (Source: American Journal of Clinical Dermatology, June 2004, pages 459-462). However, it is an unnecessary (compared to other options) and fairly strong substance to use to disinfect the skin, especially when you leave it sitting on your face in a facial mask for a period of time. There are gentler ways to disinfect the skin. Sulfur has lost its status and to some extent has been abandoned as an option for treating breakouts since the 1980s, thanks to the other successful topical choices available.