This foodstuff is also approved for therapy of wounds and burns. The activity is due to a mixture of five cysteine proteinases known as bromelain. These enzymes stimulate wound
healing by providing fibrinolytic and proteolytic activity while inhibiting thrombocyte aggregation. Bromolain also has anti-inflammatory and antineoplastic effects. The health hazards of pineapple consist of contact allergic and irritant reactions. Pineapple extract is administered as tablets or granules or in compounded topical formulations (3).