Category: Cosmetic Formulation of Skin Care Products

SOME PRACTICAL CONSIDERATIONS WHEN CHOOSING A PERSONAL CLEANSER

Dermatologists and consumers are faced with a variety of choices when recommending or selecting a personal cleansing product. The previous sections of this chapter reviewed some of the available literature that examines factors governing the interaction between surfactants and the skin from a theoretical standpoint. While many of the studies presented were not conducted under […]

Surfactant Binding to Stratum Corneum Proteins and Surfactant Penetration

Other studies also support a role for surfactant-protein interaction in the develop­ment of skin irritation. Imokawa et al. measured the specific rotation of bovine serum albumin (BSA) in the presence of surfactant to assess surfactant-protein interaction (69). Changes in the specific rotation were the result of conformational changes in BSA due to interactions with surfactant. […]

Removal of Skin Lipids (Delipidization)

As noted earlier, the hydrolipid film on the surface of the skin is important for maintaining skin health. Epidermal lipids, which serve as the “mortar” between the corneocyte “bricks” in the stratum corneum, are also important to maintaining skin health and stratum corneum barrier function (53-55). Patient populations that exhibit heightened sensitivity to personal cleansing […]