1. Science and clinical studies: Topical application of Pantothenic Acid has been shown to provide moisturizer-like benefits, improving stratum corneum hydration, reducing transepidermal water loss, and maintaining skin softness and elasticity. Activation of fibroblast proliferation, which is of relevance in wound healing, has been observed both in vitro and in vivo, and accelerated re – […]

1. Science and clinical studies: Niacinamide was evaluated clinically in Japanese women for the inhibition of pigmentation. Eighteen subjects with hyperpig­mentation received either a 5% Niacinamide containing product or a placebo. Additionally, 120 subjects with facial tanning were given either a 2% Niacinamide cream containing a sunscreen, a sunscreen, or a vehicle. Changes in facial […]

1. Science and clinical studies: Two studies have been published whereby vitamin K has been used to minimize purpura production after pulse dye laser treatments (17) . Both studies employed approximately 20 subjects, with one evaluating the effects of the ingredient alone and the other with the use of retinol BID weeks before and two […]

1. Science and clinical studies: Numerous studies have been published on both of these ingredients relating to antioxidant function and protection against UV damage. Additionally, vitamin C has been shown to enhance collagen and elastin production. Both ingredients are essential in a formula if any antioxidant and/or anti-aging claims are to be made. The two […]

Amino Filaggrin Acids—Filaggrin Protein/Fruit Acids 1. Science and clinical studies: Although no peer review articles were found, studies outlined by the manufacturer of the product claim that the product has been tested over the last three years and is effective in reducing the appearance of visible lines and improving tone and texture of the skin. […]

Numerous countries all around the world have recently instituted some form of cosmetic regulation, other than product registration with their ministries of health, with respect to protecting the consumers of their respective countries. The amount of information is massive and to simply list current activities would go far beyond the scope of this chapter. However, […]

Domestic Regulations There have been many misunderstandings relating to the regulation of cosmetic products and OTC drugs in the United States. For the most part, the cosmetic industry has never been directly regulated by any government agency and does not require the FDA to approve a cosmetic/cosmeceutical product prior to marketing. Additionally, in 1972 the […]

The skin plays many roles ranging from barrier function to highly complex biochemical and photobiochemical processes. If we follow the definition above then cosmeceuticals are inherently not simply cosmetics to beautify the appearance of the skin. Figure 1 American Academy of Dermatology Office Dispensing Guidelines for Prescription and Non-prescription Products. Source: American Academy of Dermatology, […]

The skin is the body’s first line of defense for environmental exposure. Much of the “premature” aging (in contrast to intrinsic or chronologic aging) occurs as a direct or indirect result of the skin’s interaction with its environment. While photoaging is properly recognized as one of the principal causes of aging in lighter skin types, […]