J. F. Nash and Paul R. Tanner P&G Beauty, Sharon Woods Technical Center, Cincinnati, Ohio, U. S.A. INTRODUCTION There is consensus among the scientific and medical communities that exposure to sunlight is a major factor in the etiology of the progressive unwanted changes in the appearance of skin, i. e., photoaging, and in the risk […]

There are a variety of other treatment options that have been tried with limited documented success. These treatments include such surgeries as excision of sweat glands and liposuction. It is very difficult to excise the sweat glands without creating movement problems in the armpit. The hair bearing skin typically denotes the location of the sweat […]

Anticholinergic drugs, such as Robinal, may help prevent the stimulation of the sweat glands and thus inhibit sweat output. The FDA has not approved any drug for the treatment of hyperhidrosis. Although these drugs may be effective in inhibiting excessive sweat, there are significant side effect risks with these medications. These include such effects as […]

Early surgical techniques that were used to treat hyperhidrosis were invasive, risky, scarring, and sometimes unsuccessful. Endoscopic thoracic sympathectomy (ETS) surgery is less invasive, since it is performed with the aid of a small endoscope that is introduced into the body. This surgery is designed to interrupt the transmission of nerve signals to the sweat […]

This procedure employs the use of weak electric current to slow down sweat production. It requires the purchase of a battery-operated device with a removal pad. The pad is soaked either with tap water or a dilute solution of aluminum chloride in tap water. The device is placed in the armpit and turned on for […]

Antiperspirants The treatment of hyperhidrosis with OTC antiperspirant products is usually the first method employed by those who suffer with this condition. There are no currently marketed antiperspirants that are explicitly designed or claim to have a beneficial effect on excessive sweating. As stated earlier the FDA has not approved any marketed OTC antiperspirant product […]

Hyperhidrosis is defined as excessive sweating. The profusion of sweat may be in the axillae, the palms, the feet, the face, on the trunk, or a combination of any or all of the above body parts. The excessive sweat is beyond the person’s physiological requirement to regulate the body’s temperature and is largely under emotional […]

In the U. S. the introduction of any new antiperspirant actives into the market will require a New Drug Application (NDA) or an Abbreviated New Drug Application (ANDA). These procedures will no doubt inhibit bringing new actives into the market place unless there is a strong inclination by the manufacturer to believe their new active […]

The approach taken by manufacturers to encourage compliance has been to offer a wide choice in product form and aesthetics. Today’s consumers are accustomed to a variety of choices in their antiperspirant selection. It is clear, from even a cursory glance at the antiperspirant/deodorant shelves in any supermarket or pharmacy, that there is a wide […]