In 2003 and 2004 Noni was the largest selling single herb in the U. S. It has no reliable published clinical research. Noni’s unproven uses are for many systemic diseases including diabetes, infections, fever, arthritis and wounds.
The active ingredients are iridoids including asperulosid. Topically, it is an emoltient used to reduce signs of skin aging. The active ingredients are iridoids including asperulosid, retinol, ascorbic acid, ursolic and linoleic acids (3,22).