This herb has traditionally been a hemorrhoid, skin condition, and cancer treatment and has an immune stimulant effect. Its active compounds include nigellone and thymoquinone. Black seed has antioxidant, antiphlogistic, antibacterial, and antihelminthic effects (22).
Four clinical studies documented efficacy of this herb for treatment of atopic dermatitis and asthma when administered orally. The score of subjective symptomotology in each study decreased with a p<0.05 significantly (26).