Low-level lasers have been proposed as early as 1967 by Pr. Endre Mester, in Semmel – weis University Budapest, Hungary. Forty years later, there is still much debate about the role LLLT plays in wound healing. 19.2.1 Photomodulation Photomodulation (a term very often proposed by the authors of papers on LLLT, but for which a […]

Serge Mordon INSERM & Lille University Hospital, Lille, France 19.1 Introduction 369 19.2 Low-Level Laser Therapy (LLLT) 370 19.2.1 Photomodulation 371 19.2.2 Experimental Studies 373 19.2.3 Clinical Studies 374 19.3 Light Emitting Diodes 374 19.3.1 Experimental Studies 375 19.3.2 Clinical Studies 375 19.4 Lasers 375 19.5 Conclusions 378 References 379 19.1 1 ntroduction Wound healing […]

Laser treatments for PFB including the use of ruby, alexandrite, 800 nm diode and 1080 nm Nd:YAG with and without exogenous chromophores have been evaluated at an increasing rate over the last ten years. The initial rationale for laser treatments for PFB was based on the simple assumption that lasers could achieve a rapid permanent […]

In our research at the Gillette Company Research Institute, we conducted a series of Phase I, Phase II, and Phase III studies between 1988 and 2000, evaluating the efficacy of eflorni­thine HCl in facial-hair retardation. In the first study ever conducted, the use of Eflornithine in the treatment of unwanted facial hair in women established […]

Men with the most severe cases of PFB often cannot tolerate any shaving, but men with less severe PFB who can shave daily benefit form daily shaving. Strauss and Kligman [2] determined that daily shaving was actually the most effective shaving regimen to minimize lesions in most subjects, but could worsen the condition in those […]

Recent research on the molecular biological factors underlying curly hair has demon­strated that the biological factors controlling the processes of keratin formation and region­alized localization of specific types of keratin that are associated with curly hair are represented in all curly hair fibers independent of ethnic types. The biochemical factor promoting curly hair fibers to […]

In the 1950s, the the seminal studies by Kligman and Strauss [2] established that PFB lesions are indeed caused by ingrown hair which grow out of the follicle and then renter the skin. This propensity of hair to enter skin after exiting the follicle is the result of the curva­ture of the follicle structure. The […]

Douglas Shander and Gurpreet S. Ahluwalia The Gillette Company, a wholly owned subsidiary of The P&G Company, Needham, MA, USA 17.2 Introduction 353 17.3 Etiology of PFB 355 17.4 Biochemical Factors Involved in Elaboration of Curly Hair 357 17.5 Shaving Regimens for Managing PFB 358 17.6 Treatment of PFB with Topical Eflornithine 359 17.7 Laser […]

Treatment of acne is a challenging process due to its multifarious pathogenesis. For this reason, more studies are needed to explore other possible treatments. For example, addi­tional studies are needed to find more effective ways of enhancing the delivery of ALA to its target, possibly through microdermabration, peeling, or using the ester form of ALA […]