Retinoids

Topical retinoids such as Tazorac (active ingredient tazarotene) have been shown to have a positive effect on psoriasis (Source: Cutis, January 1999, pages 41-48), particularly in combina­tion with other treatments (Source: InternationalJournal of Dermatology, January 2001, pages 64-66). Tazarotene is a synthetic acetylenic retinoid. Some research has shown it to be more effective than tretinoin (Renova and Retin-A). A positive feature of tazarotene is its ability to maintain clinical response after discontinuation of treatment. Side effects can include irrita­tion, burning, and flaking skin (Source: Journal ofthe European Academy of Dermatology and Venereology, July 2008, pages 859-870). Retinoids improve cell development and mitigate the damage caused by topical cortisones when used as a combination or alternating treatment.