Azelaic acid

Azelaic acid is a derivative of grains such as wheat, rye, and barley, yet while it has a natural origin it is created from oleochemicals (chemicals derived from oils or fats). It is considered very effective when applied topically in a cream formulation at a 15% to 20% concentration, and should be considered for a number of skin conditions. For the most part, azelaic acid is recommended as an option for acne or rosacea, but there is also some research showing it to be effective for the treatment of skin discolorations. Azelaic acid in concentrations of 15% and 20% is available by prescription only. Twenty percent azelaic acid is available by prescription only in Azelex and 15% azelaic acid is found in the prescription-only Finacea. (Sources: Journal of Dermatology, January 2007, pages 25-30; Cutis, February 2006, pages 22-24; and Medical Hypotheses, March 1999, pages 221-226.) Concentrations lower than 15% (usually less than 1%) show up in cosmetic skin-care products. When combined with other “actives” ranging from retinol to AHAs and vitamin C it can be another option when you begin experimenting to find what works for you.