Although products cannot be sold bearing an anti-acne label unless they contain an OTC approved ingredient, many botanical formulations are marketed towards the acne-prone consumer claiming to “heal,” “purify,” or “cleanse” the skin and pores. Companies promote their proprietary formula of herb extracts, but well-conducted clinical studies are lacking, and therefore it is difficult to understand the true efficacy of these products. The formulation may include different herb extracts with various activities (antimicrobial, antioxidant, anti-inflammatory, soothing, etc.).