Experimental Studies

Due to the recent introduction of powerful LED, there are a very limited number of exper­imental studies on wound healing. Al-Watban et al. have performed a study to determine the efficacy of polychromatic LED in the enhancement of wound healing in nondiabetic and diabetic rats. A polychromatic LED (a cluster of 25 diodes emitting photons at wavelengths of 510-543, 594-599, 626-639, 640-670, and 842-879 nm) therapy has been evaluated [20]. Although the effect of polychromatic LED therapy in oval full-thickness wound-healing in the diabetic model with the use of 5 and 10 J/cm2 was promising, further studies to deter­mine optimum dosimetry and efficacy of LEDs were recommended by the authors [21].